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Chadatog

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Posts posted by Chadatog

  1. On 6/22/2021 at 10:10 AM, CitizenVectron said:

     

    I think the issue is that we have no proof that plaque causes the harm, or that removing it will help. Many drugs work and we don't fully understand why, and that's good enough to get them approved. But this drug should work (theoretically) but doesn't, so it's not good enough to be approved. 

     

    A good comparison would be between Multiple Sclerosis and Vitamin D. We know that people with MS have reduced VitD levels. Is it caused by MS? Or is it a symptom of having MS? Many people, despite any evidence to the former, take huge amounts of D3, hoping it will help their MS. At least in the case of D3 it is cheap, readily available, and in reality, everyone probably needs more VitD than they get. But there is no evidence it works, even though we know low levels are associated with MS.

     

    The only thing that matters is results, and if this drug can't show that it's helpful at all (and in fact, has strong side effects), then it should never be approved. It's like, here is the entire thing distilled in terms of how it should be:

     

    Drug Company: This drug removes plaque.

    People: That's awesome! Does removing plaque improve Alzheimer's? 

    Drug Company: No

    FDA: DENIED

     

    Hopefully insurance companies and governments deny coverage for this. Unfortunately, that will likely mean people pay out of pocket in Mexico and Russia (or the US) to get their own private supply that does nothing, but still bankrupts them.

    Just listened to a great podcast that dealt with exactly this, talking to Dr. Aaron Kesselheim, one of the Dr's who resigned from the advisory panel.

     

    They are called surrogate endpoints, and in this case is the big cause of all of the problems that @CitizenVectron pointed out.

  2. 13 hours ago, Greatoneshere said:

     

    Yeah I enjoyed the anime, Voltron, giant mech, Evangelion spoofs. All the incest baby stuff isn't as funny as the show seems to think it is, and the episodes hang together rougher than they used to, but I still laughed a good bit.

    But his name is Naruto, I thought it made the incest baby storyline pay off more and think it will culminate into a classic episode

  3. On 7/30/2021 at 12:24 PM, stepee said:

     

    Since “crt” is now the name used for a white supremacist movement based around suppressing minority voices, removing their stories from America’s history, and promoting their perception of the great white race, we should just change the name of the actual critical race theory study to anything else so we can stop trying to argue it and just call anyone who talks about crt ever a white supremacist, make them scared to say it in public.

     

    How about Legal Educational Diversity

    • stepee 1
  4. 13 hours ago, SuperSpreader said:

    What they say 

    They were talking about the FBI and the 1/6 conspiracy about them honeypotting the MAGA people in to storming the capitol and talked with the dude who wrote the book on the FBI entrapping Muslims on terrorist charges, Trevor Aaronson.  After talking about how Tucker Carlson was co opting what the FBI has done to other groups to the 1/6 groups, they also talked about other groups that were on the FBI's radar and the Moors were talked about as being seen as a radical group much like sovereign citizens.

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